The Experimental Therapeutics (ETx) Core is a preclinical resource to Dana-Farber Cancer Institute (DFCI) researchers and collaborators for conducting in vivo pharmacological studies. Studies will be run at a 14,000-square-foot preclinical facility shared with the Lurie Family Imaging Center (LFIC) that features bioluminescent imaging using the IVIS Spectrum system.
Our mission is to help DFCI investigators by providing high quality in vivo pharmacology studies that enable DFCI investigators’ translational research and chemistry and drug discovery/development efforts. These include studies that determine efficacy of new therapies and new combinations, advance preclinical studies to initiate clinical trials, and target identification and validation.
The Experimental Therapeutics Core will provide expertise for in vivo pharmacology studies, including drug tolerability and efficacy studies; pharmacodynamic and mechanism-of-action studies, and tumor model development. Our capabilities include both subcutaneous and orthotopic tumor implantations and animal dosing by all common routes of administration, e.g. intraperitoneal, intravenous, oral and subcutaneous, and in combination. Comprehensive tumor and tissue harvesting is available for every study. Fresh samples can be sent to investigators or preserved by formalin fixation and/or flash freezing.
Purchase Orders are to be made out to:
Dana Farber Cancer Institute
General Accounting, BP-430
450 Brookline Avenue
Boston, MA 02215-5450
Note to Partners, Harvard, Boston Children’s and Tufts researchers etc:
If you are using a PO from an institution other than one under which you signed in, you must stop and contact the DFCI iLab staff at sc_billing@dfci.harvard.edu
Prafulla Gokhale, Ph.D., Head of the Experimental Therapeutics Core
Debbie Taylor-Nicoleau, Core Administration, Experimental Therapeutics Core
Hours | Location |
8:00 AM - 4:00 PM |
27 Dry Dock Ave, Boston, MA 02210 |
Name | Role | Phone | Location | |
---|---|---|---|---|
Debbie Taylor-Nicoleau |
Program Coordinator
|
(617) 582-8969
|
Debbie_Taylor-Nicoleau@dfci.harvard.edu
|
DD-109
|
Dr. Praful Gokhale |
Head of the Experimental Therapeutics Core
|
(617) 632-6919
|
Prafulla_Gokhale@dfci.harvard.edu
|